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IVF vs IUI โ€“ Which Fertility Treatment is Right for You?

February 2025  ยท  Dr. Ankita Mandal, MD (OBGYN)

๐Ÿ“Œ Quick Answer

IUI (Intrauterine Insemination) is a simpler, less invasive, and cheaper procedure (โ‚น10,000โ€“โ‚น25,000) suitable for mild infertility. IVF is more complex and expensive (โ‚น90,000โ€“โ‚น2,00,000) but has significantly higher success rates and is recommended for severe infertility, tubal blockage, male factor infertility, or advanced age. Most couples with complex infertility skip IUI and go directly to IVF.

Head-to-Head Comparison: IVF vs IUI

Factor IUI IVF
Invasiveness Minimal (no surgery) Moderate (egg retrieval under sedation)
Success Rate (per cycle) 10โ€“20% 40โ€“70% (depends on age)
Cost per Cycle โ‚น10,000โ€“โ‚น25,000 โ‚น90,000โ€“โ‚น2,00,000
Duration 1โ€“2 weeks 4โ€“6 weeks
Sperm Requirement Moderate motility needed Works with very low sperm count (ICSI)
Blocked Tubes Cannot be used Bypasses tubes completely
Genetic Testing Not possible PGT-A possible for embryo screening
Multiple Pregnancy Risk Moderate (if multiple follicles) Controlled (elective single embryo transfer)
Best For Unexplained infertility, mild male factor, ovulation issues Tubal blockage, severe male factor, age 35+, repeated IUI failure

When to Choose IUI

  • Under 35, trying for less than 2 years
  • Mild male factor infertility (moderately reduced sperm count or motility)
  • Unexplained infertility with open fallopian tubes
  • Ovulation disorders (PCOS responding to medication)
  • Donor sperm is being used

When to Skip IUI and Go Directly to IVF

  • Age 35 or above (time matters โ€” don't waste it on lower-success IUI)
  • Blocked or damaged fallopian tubes
  • Severe male factor infertility (very low count, motility, or abnormal morphology)
  • Endometriosis (moderate to severe)
  • Failed 3+ IUI cycles
  • Need for PGT genetic testing
  • Low ovarian reserve (low AMH)

The Cost Reality: IUI Cheaper but Lower Success

While IUI appears cheaper per cycle (โ‚น10,000โ€“โ‚น25,000 vs โ‚น90,000+ for IVF), the cumulative cost of multiple failed IUI cycles before switching to IVF can equal or exceed an IVF cycle. If you have clear indicators for IVF, starting directly saves time, cost, and emotional energy.

Not Sure Which Treatment is Right for You?

Get a personalized recommendation from Dr. Ankita Mandal based on your specific diagnosis and fertility profile.

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